Soft Tissue Sarcoma

Soft Tissue Sarcoma

Sarcoma is a general term covering a broad group of cancers originating from the bones or the connective tissues called soft tissue sarcoma. Soft tissue sarcomas develop in the tissues that connect, support and surround other structures of the body, including muscles, fat, blood vessels, nerves, tendons and the lining of the joints.

Sarcomas are of more than 70 types. Their treatment depends on their type, location, and several other factors.

  • Angiosarcoma
    It is the cancer of the inner lining of the blood and lymph vessels.
  • Chondrosarcoma
    It is a rare form of cancer that originates from the bones but can sometimes spread to the surrounding tissues.
  • Dermatofibrosarcoma protuberans
    It is cancer that originates from the connective tissue in the middle layer of the skin called the dermis.
  • Desmoplastic small round cell tumours
    It is a type of soft tissue sarcoma originating from the abdomen or the pelvic area of the body.
  • Epithelioid sarcoma
    This soft tissue cancer mostly begins in the soft tissue beneath the skin of a finger, hand, forearm, leg, or foot.
  • Ewing sarcoma
    This cancer is typically seen in children and young adults. It starts in the legs, pelvic bones, or arms.
  • Gastrointestinal stromal tumour (GIST)
    This tumour is found in the walls of the digestive organs.
  • Kaposi's sarcoma
    This type of cancer typically affects immunocompromised individuals like HIV patients. It causes lesions in soft tissues such as the skin, lymph nodes, and mucous membranes lining the mouth, nasal cavity, and throat.
  • Leiomyosarcoma
    It is a cancer of the smooth muscles.
  • Liposarcoma
    It is a cancer of cells of the body, most commonly of the limbs or the abdomen.
  • Malignant peripheral nerve sheath tumours
    It is the cancer of the sheath or lining covering the peripheral nerves.
  • Myxofibrosarcoma
    It is cancer that starts in the connective tissue of the arms and legs.
  • Osteosarcoma
    It is a type of sarcoma affecting the bones, most commonly the long bones of the arms and the legs.
  • Rhabdomyosarcoma
    It is the cancer of the skeletal muscle tissue or hollow organs like the uterus or the bladder.
  • Solitary fibrous tumour
    These soft tissue tumours can develop anywhere in the body, most commonly in the lining covering the lungs.
  • Synovial sarcoma
    This type of sarcoma can start from different soft tissues, including those of the arms, legs, foot, lungs or abdomen.
  • A lump or painless lump that can be felt through the skin
  • Pain in the abdomen
  • Unexplained weight loss

The cause of most sarcomas is unknown. However, most cancers form due to DNA mutations within the cells. Normally, the cell's DNA instructs it to carry out its functions properly. When the DNA is damaged, it is unable to direct the cell and regulate its functions. This results in uncontrolled proliferation of the cells, which accumulate and give rise to a tumour. Sometimes these abnormal cells can spread to other parts of the body through the bloodstream or the lymphatic system.

  • Inherited conditions
    Some inherited syndromes such as familial retinoblastoma and neurofibromatosis type 1 increase the risk of such cancers.
  • Previous exposure to radiation therapy
    People who have been exposed to radiation for the treatment of cancers previously have an increased risk of developing sarcomas later.
  • Lymphedema
    It is a long-standing swelling caused due to the accumulation of lymphatic fluid secondary to obstruction in the lymphatic system.
  • Exposure to toxic substances
    Exposure to certain chemicals, like some industrial chemicals and herbicides, can increase the chances of developing a sarcoma affecting the liver.
  • Exposure to viruses:
    Infection by human herpesvirus 8 can increase the risk of developing Kaposi's sarcoma, a type of sarcoma that occurs in people with weakened immune systems.

Certain tests are used for the diagnosis of sarcoma and to determine their stage and the extent of spread.

  • Physical examination
    A complete body examination is conducted to understand the symptoms better and look for other clues to support the diagnosis.
  • Imaging tests
    The types of imaging tests performed depend upon the situation of the patient and the symptoms. If a bone disease is suspected, X-rays are better for diagnosing them. For connective tissue or soft tissue diseases, MRI is a better choice. Other imaging tests such as ultrasound, PET scan, and bone scans may be done for staging.
  • Biopsy
    It involves the resection of a sample of the suspected tissue with the help of a needle or during an operation and sending it for histopathological examination. It is usually done for cases highly suspected of malignancy.

If you are finding the best Soft Tissue Sarcoma treatment in Navi Mumbai, your search is over. Kokilaben Dhirubhai Ambani Hospital is the best hospital for Treatment of Soft Tissue Sarcoma in Navi Mumbai. The treatment plan is prepared and delivered by a team of expert doctors who have years of experience in treating these cancers.

Surgery is the first treatment option considered for most sarcomas. Other treatment options may be used in combination with surgery to gain better outcomes. The treatment plan depends on the variant, location, and extent of the spread of cancer.

  • Surgery
    The goal of surgery is to remove the cancer cells as much as possible. Surgeons always try to employ minimally invasive techniques and preserve the body organs but sometimes it's indispensable to amputate an arm or leg to remove all of the cancer and control its spread.
  • Radiation therapy
    It uses high-energy rays from sources such as X-rays or photons to penetrate and destroy cancer cells. Radiation therapy may be given in the form of external beam radiation, brachytherapy, or intraoperatively. The rays come from a machine that revolves around the body directing the energy beam towards the targeted area during external beam radiation. Brachytherapy refers to the placement of the radiation in the body temporarily.
  • Chemotherapy
    This therapy uses specialized drugs called chemotherapeutic agents to destroy cancer cells. Some types of soft tissue sarcomas respond more to chemotherapy than others.
  • Targeted therapy
    This therapy makes use of drugs to specifically target the cancer cells while sparing the normal cells of the body.
  • Immunotherapy
    This drug therapy stimulates the body's immune system to fight the cancer cells more effectively. Sometimes the cancer cells produce special proteins that protect them from the body's immune system. Immunotherapy works by interfering with those proteins, thus making the cancer cells susceptible to damage.
  • Ablation therapy
    During this treatment procedure, the cancer cells are subjected to very high temperatures so that they burn and get destroyed.
  • Cryotherapy
    The cancer cells are subjected to very low temperatures that freeze them and cause their destruction.

We at Kokilaben Dhirubhai Ambani Hospital, Navi Mumbai acknowledge that cancer diagnosis comes with endless uncertainty and distress, but you will find what helps you cope with these negative feelings with time. Until then, you may help yourself by learning enough about cancer you have and looking at the various treatment options and their prognosis. You can enquire from your doctor about your condition, including your test results and decisions about the treatment options. It may help you be more confident in making decisions about the treatment plan. You can also join some support groups and meet with people suffering from or who have recovered from the same cancer as you. Keep your friends, and family members close and do not hesitate to share your emotional problems with them. Also, do not hesitate to share your symptoms and mental health problems with the oncology team at our hospital throughout the treatment journey. There are medicines available for every symptom, so you do not need to tolerate those unnecessarily. The Sarcoma Treatment at Kokilaben Dhirubhai Ambani Hospital, Navi Mumbai aims not only to treat your physical symptoms but also to ensure your mental and emotional well being at all times.